Chemical name: 1-Propanol, 2,3-dibromo-, phosphate (3:1) Final regulatory action has been taken for the category: Industrial Final regulatory action: The chemical is Banned Use or uses prohibited by the final regulatory action: Tris (2,3-dibromopropyl) phosphate may not be used in textile articles intended to come in contact with the skin. Use or uses that remain allowed: All other uses than the use in textile articles intended to come into contact with the skin are continued. The final regulatory action was based on a risk or hazard evaluation: No Summary of the final regulatory action: Tris (2,3-dibromopropyl) phosphate may not be used for the production of textile articles (clothes, underwear, bedclothes etc.) to come in contact with the human skin. The reasons for the final regulatory action were relevant to: Human health Summary of known hazards and risks to human health: Chronic Toxicity: IARC classification 2A, sufficient evidence for carcinogenicity to animals, probably carcinogenic to humans. Extra risk for cancer 10-5 at life time exposure to 10 /ug/kg b.w. (skin, 3x/week, linear extrapolation from mouse data) Epidemiological Studies: Retrospective mortality study of employees exposed to Tris or DDT. No significant overall or cause-specific mortality excess. Occupational/Use: According to a 1974 national occupational hazard survey (NIOSH) workers in the telephone communication industry are the category primarily exposed. Tris is widely used in textiles for childrens sleepwear. Estimated intake via skin: 9 /ug/kg b.w./day. Over a six year period, 2-77 mg/kg may be absorbed. Summary of known hazards and risks to the environment: . Date of entry into force of the final regulatory action: 01/01/2001 |